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Many of the side effects can be avoided by increasing water consumption and avoiding caffeine

An overview on the insulin-like growth factors (IGFs) functions in granulosa cells There is evidence that IGF function, in combination with gonadotropins such as FSH and LH, has a synergistic effect on the proliferation and promotion of theca and granulosa cells

Conclusion : Our study suggests that single topic audits organised by a medical audit advisory group can encourage large numbers of general practitioners to participate and can bring about changes in behaviour resulting in improvements in standards of care